Dr. Zahid Yaqoob, Senior Scientist at the Laser Biomedical Research Center, MIT, USA, delivered a talk on "Biophotonic systems design and applications" at CIIT Lahore on 4 August 2016.
Dr. Zahid Yaqoob, Senior Scientist at the Laser Biomedical Research Center, MIT, USA and adjunct Professor at the COMSATS Institute of Information Technology (CIIT), Islamabad is delivering a talk on "Biophotonic systems design and applications"
Venue and Date
Seminar room Block A
COMSATS Institute of Information Technology 1.5 KM Defence Road, Off Raiwind Road Lahore Pakistan
Thursday August 4 2016 at 10:30 A.M.
Biophotonics is an interdisciplinary science of utilizing light to image, probe and manipulate biological media. Over the last few decades, the field has expanded greatly due to the advances in light sources, optical components, and detectors. In spectroscopy and imaging applications, the goal is to study various physiological or pathological processes at the cellular and / or tissue level, which lead to structural and functional changes manifested in the biophysical or biochemical properties of the sample under study. Some of the key examples include retinal detachment during macular degeneration, changes in shape and size during cell growth, compromised host red blood cell mechanics during malaria infection, and damage induced by genotoxic anti-cancer drugs to the DNA in living cells. To retrieve specific biophysical or biochemical information from a biological sample, it is vital to first identify the appropriate light-matter interaction (e.g., absorption, fluorescence, scattering, etc.), which follows instrumentation design while considering the desired parameters such as optical resolution, contrast, sensitivity, throughput, and signal-to-noise or signal-to-background ratio. In this talk, I will provide an overview of selected research projects in biophotonic instrumentation and their applications including the design and development of optical coherence tomography for depth-resolved tissue imaging, quantitative phase microscopy for label-free structural and functional imaging of biological cells, and wavefront optimization for imaging through turbid media.