Nanomaterials, Natural compounds & Biopolymers for Bone Regeneration

Nanomaterials for Hard Tissue Engineering

We utilize a low-temperature flow system (LTFS) for the synthesis of biologically active metallic oxides and their use in the controlled doping of ZnO nanoparticles with therapeutic ions. Ions such as cerium, iron, calcium, magnesium, copper, potassium, and zirconium are incorporated to tailor material properties for specific biological responses. These engineered nanomaterials are being developed for applications including dental implants, bone fillers, and other biomedical additives, aiming to enhance integration and therapeutic effects in hard tissue engineering.

Nanotherapeutics for Cancer

We engineer RNA-based nanoparticles designed to precisely target and regress cancer. This research offers a potentially groundbreaking approach in cancer therapeutics by leveraging nanotechnology for targeted treatment delivery.

Nanomaterials for Drug Delivery:

Nanomaterials are doped with specific ions (Ca, Mg, etc.) to act as carriers for drugs (like IFO) or other therapeutic molecules for targeted delivery in applications ranging from cancer therapy to tissue engineering.

Natural Products and biological active loaded Bone Regenerative materials

We developed chitosan-coated alginate microspheres loaded with spirulina extract, hydroxyapatite, and metronidazole for periodontitis treatment. Fabricated via ionotropic gelation, the optimal formulation showed excellent drug loading and sustained release capabilities. These microspheres demonstrated antibacterial, antioxidant, hemocompatible, and cytocompatible properties. Notably, this formulation promoted rapid wound healing, enhanced angiogenesis, and reduced inflammation, making it a promising multifunctional platform for localized bone and periodontitis therapy

Related Areas