NatDura

Synthetic Dura Mater Substitute

Dural Substitute Watertight Closure Patented (401/2025-PPO)

NatDura is an electrospun biocompatible and biodegradable dural substitute patch designed to protect neural tissues and support watertight closure. It prevents cerebrospinal fluid (CSF) leakage, minimizes adhesion, and degradably guides the regrowth of natural dural tissues.

NatDura

Description

NatDura is an electrospun biocompatible and biodegradable dural substitute patch designed to protect neural tissues and support watertight closure. It prevents cerebrospinal fluid (CSF) leakage, minimizes adhesion, and degradably guides the regrowth of natural dural tissues.

Available Sizes
  • 4 cm x 4 cm 150,000 PKR

Advanced Dural Applications


Cranial Duraplasty

Watertight closure of dura mater after craniotomies and skull tumor removals.

Spinal Dura Repair

Sealant patch for spinal meningomyelocele or trauma-induced dural tears.

CSF Leak Prevention

Provides a mechanical barrier preventing critical cerebrospinal fluid leakage.

Adhesion Prevention

Prevents post-operative adhesions between brain parenchyma and overlying bone.

Neurosurgery Trauma

Fast closure substitute in military and civilian cranial gunshot trauma.

Tumor Resections

Fills dural voids left after aggressive meningioma resections.

Technology Status & Commercialization

Patent Status: 401/2025-PPO. DRAP Class III approval and clinical trials required. Quality compliance targets ISO 13485, ISO 14644, and ISO 10993.

Business Potential

Market Valuation

Global dural substitute market valued at USD 175.6M in 2020 and expected to hit USD 328.6M by 2031 (CAGR 5.9%).

Import Substitution

Cuts neurosurgery hospital costs by replacing imported patches costing over $1,000.

High Profit Margins

Electrospun synthesis enables high returns on capital investments.

Watertight & Suturable Controlled Bio-Degradation ISO 13485 Compliant

Principal Investigator

Dr. Hamad Khalid

Associate Professor
Member of Soft Tissue Research Group

IRCBM - CUI Lahore Campus

hamadkhalid@cuilahore.edu.pk

Research Group