Dr. Akhtar Hayat
Associate Professor, IRCBM
Area of Interest: N/A
Tel # (Off): 111-001-007  

Brief Biography

Dr Akhtar Hayat is the founder of sensors/biosensors research group at IRCBM, COMSATS, Lahore, and acting as a head of this group. Dr Akhtar was the first person to initiate and establish a bio(sensing) group in Pakistan: an extremely active and advanced area in the field of environmental, medical/ agro-food research. Dr Akhtar Hayat has licensed a patent technology with Eco global foods and working on many other applied project with commercial impact. Dr Akhtar Hayat is playing a key role towards the development of this group based on his international collaborations and national research funding.  Dr Akhtar Hayat has developed several productive research collaborations/singed research MoU with the leading research groups all over the world. He is also very progressive for working in collaboration with research groups from National Institution in Pakistan. Dr Akhtar Hayat has published various research articles in the prominent and prestigious international journals including Advanced Health Care Materials, NanoScale, Analytical Chemistry and Biosensors&bioelectronics. He is also author of many international book chapters, as well as PI for many research grants.
 
International Affiliation/visits
1. 25 June-01 July 2019: Collaborative research visits ECUST, Shanghai Polytechnic University and Qilu University of Technology CHINA
2. 1 Dec-10 Dec 2018: Visiting scientist at Universite de perpignan, France
3. 17 Dec-31 Dec 2017: Visiting scientist at cumhuriyet university, sivas/Turkey
4. 20 Nov-31 Nov 2017: Visiting scientist at Universite de Perpignan, France
5. Jan 2017: Visiting scientist at University of Sheffield, UK
6. Oct-Dec 2016: Visiting scientist at Universite de Perpignan, France
7. Feb-April 2016: Visiting scientist at Universite de Perpignan, France
8. Sept-Dec 2015: Visiting scientist at Clarkson University, USA
9. Sept-Nov 2014: Visiting Scientist at Universite de Perpignan, France
10. June-Sept 2014: Visiting Scientist at Clarkson University, USA
11. Jan 2012: Visiting Researcher at institut Européen des Membranes, UMR 5635, ENSCM-UMII- CNRS, Montpellier, France
12. Oct 2011: Visiting Researcher at Damietta branch, Mansoura University, Egypt
13. Sep 2009: Visiting Researcher at l’institut de Recerca I Technologia Agroalimentàries- Sant Carles de la Ràpita, Spain
 
Professional Honors and Awards
1. Young Scientist paper award at conference on Analytical and Nanoanalytical Methods for Biomedical and environmental Sciences Brasov/ Romania, 2012.
2. Best poster award at Eastern Analytical Symposium (EAS, November 2015, Somerset New Jersey, USA.
3. Best Poster award at 11th Workshop on Biosensors and Bioanalytical Microtechniques in Environmental and Clinical Analysis (BBMEC-11), Germany.
4. Best Poster award at International Symposium in Electroanalytical Chemistry (ISEAC), Changchun, China, 2015.
5. Best Oral Presentation award at SURE Clarkson University New York, USA; 2013.
6. Best Poster award at Indo-UK international workshop on advanced materials and their applications in nanotechnology (AMAN 2016), India.
7. Best Poster award at 2nd International Conference on Drug Development-Natural and Synthetic 2015, Abbotabad, Pakistan
8. Best poster award at conference on Analytical and Nanoanalytical Methods for Biomedical and environmental Sciences Brasov/ Romania, 2010.
9. Best poster award at 1st international symposium on "Advances in Chemistry, Polymer Science and Biomedical Materials",(ISAC' 19), 24-26 September, 2019, Islamabad, Pakistan.
10. Invited lecture on Biomimetic technology for the efficient valorization of lignin waste from woody biomass for increased biofuels production, at Pulp and paper roundtable, State university of New York College of Environmental Science and Forestry, USA, August 2013.
11. The manuscript entitled, Development of an efficient protein phosphatase-based colorimetric test for okadaic acid detection accepted in Analytica Chimica Acta was published as “Featured article” due to its high quality.
12. The articles” ssDNA Functionalized Nanoceria: A Redox Active Aptaswitch for Biomolecular Recognition represented as Cover Page of the journal Advanced healthcare materials, 2016.
13. The articles” Development of a portable and disposable NS1 based electrochemical immunosensor for early diagnosis of dengue virus represented as Cover Page of the journal Analytica Chimica Acta, 2018.
14. Awarded merit certificate for the first position in Chemistry and Zoology in B.Sc, University of Sargodha, session 2004.
15. Awarded MS and PhD scholarships for France by HEC Pakistan
16. Post doc fellowship by Clarkson university NY USA
Research Productivity Awards
1. Pakistan Council for Science and Technology award 2015
2. Pakistan Council for Science and Technology award 2016
3. Pakistan Council for Science and Technology award 2017
4. COMSATS RPA award 2014-2015
5. COMSATS RPA award 2015-2016
6. COMSATS RPA award 2016-2017

Patents

  1. Akhtar Hayat, A portable single unit device for Ochratoxin A toxicity analysis for rice quality monitoring, Pakistan patent application no 584/2019, National (Pakistan)
  2. Akhtar Hayat; Colorimetric filter paper assay for rapid monitoring of cholesterol level; USPTO patent application no 15991572. International (US patent)
  3. Akhtar Hayat; Colorimetric filter paper assay for rapid monitoring of cholesterol level; Pakistan patent application no 408/2017. National (Pakistan)

Participation in international projects

  1. Participated in the research project supported by NIH funding agency of USA, aimed to explore nanoparticles for biosensing applications
  2. Participated in the research project Alarmtox , which was collaborated between four partners from two countries; France (IMAGES, UPVD; CRITT, Toulouse) ; Spain IIQAB-CSIC, Barcelone; IRTA, Sant Carles de la Rapita)
  3. Participated in  the  research  project  Bioka,  which  was  collaborated  between  four partners  of  two  countries;  France  (IMAGES,  UPVD;     PBS,  Toulouse),  Spain (INKOA, Erandio;  IRTA, Sant Carles de la Rapita)
  4. Participated in the research project IMHOTEP , which was proposed by partners from two countries ;France (IMAGES, UPVD), and Egypt (Electroanalytical lab, Mansoura university, Damietta)
  5. Participated in the research project Demitox , Which was proposed by three partners; IMAGES, UPVD; La Rég

Publications:

Book Chapters:
1. A. Sassolas, A. Hayat, J-L. Marty (2014), "Electrochemical biosensors for the detection of microcystins : recent advances and perspectives", Electrochemical sensors and biosensors for environmental monitoring, edited by: Margarita Stoytcheva   
2. A. Hayat, H. Kanso, L. Barthelmebs (2012), "Electrochemical aptasensors for biomedical applications", Biomedical Applications of Aptamers, edited by: J.G. Bruno   
3. A. Sassolas, A. Hayat, J-L. Marty (2012), "Enzyme immobilization by entrapment within a gel network", Immobilization of enzymes and cells, edited by: Jose M. Guisan   
4. A. Hayat, A. Sassolas, A. Rhouati, J-L. Marty, (2012), "Immobilization of enzyme on ethynyl-modified electrodes via click chemistry", Immobilization of enzymes and cells, edited by: Jose M. Guisan   
5. A. Sassolas, A. Hayat, J-L. Marty (2012), "Immobilization of enzymes on magnetic beads through affinity interactions", Immobilization of enzymes and cells, edited by: Jose M. Guisan   
6. A. Hayat, L. Barthelmebs (2011), "Analytical Methods for the Detection of Ochratoxin A in Wines", Wine: Types, Production and Health, Food Science and Technology, edited by: Arthur S. Peeters   
Journal Papers:
1. Reem Khan, Abdur Rehman, Akhtar Hayat, Silvana Andreescu (2019), "Magnetic particles-based analytical platforms for food safety monitoring", Magnetochemistry, DOI: https://doi.org/10.3390/magnetochemistry5040063, Impact Factor: 2.19   
2. K Yugender Goud, V Sunil Kumar, Akhtar Hayat, Gaelle Catanante, K Vengatajalabathy Gobi, Jean Louis Marty (2019), "Polymer scaffold layers of screen-printed electrodes for homogeneous deposition of silver nanoparticles: Application to the amperometric detection of hydrogen peroxide", Microchimica Acta, DOI: https://doi.org/10.1007/s00604-019-3963-y, Impact Factor: 5.83   
3. Aftab Ahmed, Peter John, Mian Hasnain Nawaz, Akhtar Hayat, Muhammad Nasir (2019), "Zinc-doped mesoporous graphitic carbon nitride for colorimetric detection of hydrogen peroxide", ACS Applied Nano Materials, DOI: https://doi.org/10.1021/acsanm.9b01036, Impact Factor: 5.09   
4. Razia Batool, Muhammad Asim Akhtar, Akhtar Hayat, Dongxue Han, Li Niu, Muhammad Ashfaq Ahmad, Mian Hasnain Nawaz (2019), "A nanocomposite prepared from magnetite nanoparticles, polyaniline and carboxy-modified graphene oxide for non-enzymatic sensing of glucose", Microchimica Acta, DOI: https://doi.org/10.1007/s00604-019-3364-2, Impact Factor: 5.83   
5. Razia Batool, Amina Rhouati, Mian Hasnain Nawaz, Akhtar Hayat, Jean Louis Marty (2019), "A review of the construction of nano-hybrids for electrochemical biosensing of glucose", Biosensors, DOI: https://doi.org/10.3390/bios9010046, Impact Factor: 5.5   
6. Muhammad Asim Akhtar, Razia Batool, Akhtar Hayat, Dongxue Han, Sara Riaz, Shifa Ullah Khan, Muhammad Nasir, Mian Hasnain Nawaz, Li Niu (2019), "Functionalized graphene oxide bridging between enzyme and Au-sputtered screen-printed interface for glucose detection", ACS Applied Nano Materials, DOI: https://doi.org/10.1021/acsanm.9b00041, Impact Factor: 5.09   
7. K Yugender Goud, V Sunil Kumar, Akhtar Hayat, K Vengatajalabathy Gobi, Hocheol Song, Ki-Hyun Kim, Jean Louis Marty (2019), "A highly sensitive electrochemical immunosensor for zearalenone using screen-printed disposable electrodes", Journal of Electroanalytical Chemistry, DOI: https://doi.org/10.1016/j.jelechem.2018.10.058, Impact Factor: 4.464   
8. Reem Khan, Sondes Ben Aissa, Tauqir A Sherazi, Gaelle Catanante, Akhtar Hayat, Jean Louis Marty (2019), "Development of an impedimetric aptasensor for label free detection of patulin in apple juice", Molecules, DOI: https://doi.org/10.3390/molecules24061017, Impact Factor: 4.412   
9. Amina Rhouati, Marjan Majdinasab, Akhtar Hayat (2018), "A perspective on non-enzymatic electrochemical nanosensors for direct detection of pesticides", Current Opinion in Electrochemistry, DOI: https://doi.org/10.1016/j.coelec.2018.06.013, Impact Factor: 7.27   
10. Marjan Majdinasab, Akhtar Hayat, Jean Louis Marty (2018), "Aptamer-based assays and aptasensors for detection of pathogenic bacteria in food samples", TrAC Trends in Analytical Chemistry, DOI: https://doi.org/10.1016/j.trac.2018.07.016, Impact Factor: 12.3   
11. Mian Hasnain Nawaz, Akhtar Hayat, Gaelle Catanante, Usman Latif, Jean Louis Marty (2018), "Development of a portable and disposable NS1 based electrochemical immunosensor for early diagnosis of dengue virus", Analytica chimica acta, DOI: https://doi.org/10.1016/j.aca.2018.04.032, Impact Factor: 6.55   
12. Rupesh K Mishra, Amina Rhouati, Diana Bueno, Muhammad Waqas Anwar, Shakir Ahmad Shahid, Vinay Sharma, Jean Louis Marty, Akhtar Hayat (2018), "Design of a portable luminescence bio-tool for on-site analysis of heavy metals in water samples", International Journal of Environmental Analytical Chemistry, DOI: https://doi.org/10.1080/03067319.2018.1521395, Impact Factor: 2.83   
13. Muhammad Azhar Hayat Nawaz, Marjan Majdinasab, Usman Latif, Muhammad Nasir, Gultekin Gokce, Muhammad Waqas Anwar, Akhtar Hayat (2018), "Development of a disposable electrochemical sensor for detection of cholesterol using differential pulse voltammetry", Journal of pharmaceutical and biomedical analysis, DOI: https://doi.org/10.1016/j.jpba.2018.07.005, Impact Factor: 3.94   
14. Ali Othman, Akhtar Hayat, Silvana Andreescu (2018), "Eu-doped ceria nanocrystals as nanoenzyme fluorescent probes for biosensing", ACS Applied Nano Materials, DOI: https://doi.org/10.1021/acsanm.8b01345, Impact Factor: 5.09   
15. Sajid Rauf, Yaqeen Ali, Sabir Hussain, Fakhar Ullah, Akhtar Hayat (2018), "Design of a novel filter paper based construct for rapid analysis of acetone", PloS one, DOI: https://doi.org/10.1371/journal.pone.0199978, Impact Factor: 3.24   
16. Faiza Zarif, Sajid Rauf, Muhammad Zahid Qureshi, Noor Samad Shah, Akhtar Hayat, Nawshad Muhammad, Abdur Rahim, Mian Hasnain Nawaz, Muhammad Nasir (2018), "Ionic liquid coated iron nanoparticles are promising peroxidase mimics for optical determination of H 2 O 2", Microchimica Acta, DOI: https://doi.org/10.1007/s00604-018-2841-3, Impact Factor: 6.62   
17. Atul Sharma, Reem Khan, Gaelle Catanante, Tauqir A Sherazi, Sunil Bhand, Akhtar Hayat, Jean Louis Marty (2018), "Designed strategies for fluorescence-based biosensors for the detection of mycotoxins", Toxins, DOI: https://doi.org/10.3390/toxins10050197, Impact Factor: 4.55   
18. Mian Hasnain Nawaz, Gaelle Catanante, Jean Louis Marty, Akhtar Hayat (2018), "One step growth of electro-assisted BSA functionalized screen-printed carbon interface with improved antifouling characteristics", Journal of Electroanalytical Chemistry, DOI: https://doi.org/10.1016/j.jelechem.2018.03.047, Impact Factor: 4.46   
19. Sajid Rauf, Geetesh K Mishra, Jahanzaib Azhar, Rupesh K Mishra, K Yugender Goud, Muhammad Azhar Hayat Nawaz, Jean Louis Marty, Akhtar Hayat (2018), "Carboxylic group riched graphene oxide based disposable electrochemical immunosensor for cancer biomarker detection", Analytical biochemistry, DOI: https://doi.org/10.1016/j.ab.2018.01.007, Impact Factor: 3.37   
20. Gonca Bülbül, Akhtar Hayat, Fatima Mustafa, Silvana Andreescu (2018), "DNA assay based on nanoceria as fluorescence quenchers (nanoceracq DNA assay)", Scientific reports, pp: 1-9, Vol: 8, Issue: 1, DOI: DOI:10.1038/s41598-018-20659-9, Impact Factor: 4.379    (External URL)
21. Alina Vasilescu, Akhtar Hayat, Szilveszter Gáspár, Jean-Louis Marty (2018), "Advantages of carbon nanomaterials in electrochemical aptasensors for food analysis", Electroanalysis, pp: 2-19, Vol: 30, Issue: 1, DOI: https://doi.org/10.1002/elan.201700578, Impact Factor: 3.22    (External URL)
22. Amina Rhouati, Muhammad Nasir, Jean-Louis Marty, Akhtar Hayat (2018), "Photoinduced discharge of electrons stored in a TiO2-MWCNT composite to an analyte: application to the fluorometric determination of hydrogen peroxide, glucose and aflatoxin B1", Microchimica Acta, pp: 1-9, Vol: 185, Issue: 1, DOI: https://doi.org/10.1007/s00604-017-2583-7), Impact Factor: 5.83    (External URL)
23. A.Hayat, J.L, Marty (2014) (2014), "Aptamer based electrochemical sensors for emerging environmental pollutants monitoring, preprint", Special Topics in Chemistry Research   
24. . G.S. Nunes, J.A.P. Lins, F.G.S. Silva, L.C. Araujo, F.E.P.S. Silva, C.D. Mendonça, M. Badea, A. Hayat, J.-L. Marty (2014), "Design of a macroalgae amperometric biosensor; application to the rapid monitoring of organophosphate insecticides in an agroecosystem", Anal and Bioanal Chem, Impact Factor: 3.64   
25. I.Bakas,A. Hayat. R.Roullion. T.Nougher (2014), "Design of a MIP/sol gel based platform for insecticides detection in water samples", Biosensors and Bioelectronics, Impact Factor: 5.43   
26. A.Hayat, J.L, Marty (2014), "Disposable screen printed electrochemical sensors: tools for environmental monitoring,Submitted", Sensors, Impact Factor: 1.953   
27. A. Hayat, S. Andreescu (2014), "Nanoceria particles as catalytic amplifiers for alkaline phosphatase assays", Analytical Chemistry, pp: 10028-10032, Vol: 85(21), Impact Factor: 5.695   
28. W. Haider, S. Delahaie, J. François , A. Hayat, D. Barillier, J. Ledauphin (2014), "Physicochemical characterization of Pommeau de Normandie: Establishing a relationship between metal contents and turbidity of the Pommeau samples, submitted", European food research and technology, Impact Factor: 1.43   
29. A. Hayat, G.Bulbul, S. Andreescu (2014), "Probing phosphatase activity using redox active nanoparticles: A novel colorimetric approach for the detection of enzyme activity", Biosensors and Bioelectronics, pp: 334–339, Vol: 56, Impact Factor: 5.43   
30. R-E. Ozel, A. Hayat, S. Andreescu (2014), "Recent advances in analytical techniques for the measurement of neurotransmitters,preprint", Analytical letters, Impact Factor: 0.9   
31. A, Hayat, D, Andreescu, G,Bulbul, S, Andreescu (2014), "Redox reactivity of cerium oxide nanoparticles against dopamine", Journal of Colloid and Interface Science, pp: 240–245, Vol: 418, Impact Factor: 3.172   
32. A. Hayat, J. Cunningham, S. Andreescu (2014), "Spectroscopic study of the oxidase like activity of biomimetic nanoparticles, and application to detection of dopamine and catechol", Anal Chim Acta, Impact Factor: 4.387   
33. A. Rhoutai, A. Hayat, C. Yang, J-L. Marty (2013), "Aptamers: a promising tool for Ochratoxin A detection in food analysis", Toxins, Impact Factor: 2.192   
34. N. Paniel, J. Baudart, A. Hayat, L. Barthelmebs (2013), "Aptasensor and genosensor methods for detection of microbes in real world samples", Methods, Impact Factor: 3.641   
35. A. Hayat, S. Andreescu, J-L. Marty (2013), "Design of PEG-Aptamer two piece macromolecules as convenient and integrated sensing platform: application to the label free detection of small size molecules", Biosensors and Bioelectronics, pp: 168-173, Vol: 45, Impact Factor: 5.43   
36. A. Sassolas, A. Hayat, G. Catanante, J-L. Marty (2013), "Detection of the marine toxin okadaic acid: assessing seafood safety", Talanta, Impact Factor: 3.498   
37. A. Rhoutai, A. Hayat, D-B. Hernandez, Z. Meraihi, R. Munoz, j-L. Marty (2013), "Development of an automated flow-based electrochemical aptasensor for on-line detection of OTA", Sens. actuat. B, Impact Factor: 3.535   
38. A. Hayat, R-E. Ozel, K-N. Wallace, S. Andreescu (2013), "Effect of cerium oxide nanoparticles on intestinal serotonin in zebrafish", RSC Advances, pp: 15298-15309, Vol: 3, Impact Factor: 2.562 (Partial)   
39. A. Hayat, W. Haider, M. Rolland, J-L. Marty (2013), "Electrochemical grafting of long spacer arms of hexamethyldiamine on screen printed carbon electrode surface: application in target induced ochratoxin A electrochemical aptasensor", Analyst, Impact Factor: 3.969   
40. A Hayat, A. Sassolas, J-L. Marty, A-E. Radi (2013), "Highly sensitive ochratoxin A impedimetric aptasensor based on the immobilization of azido-aptamer onto electrografted binary film via click chemistry", Talanta, Impact Factor: 3.498    
41. A. Sassolas, G. Catanante, A. Hayat, L-D. stewart, C-T. Elliott, J-L. Marty, (2013), "Improvement of the efficiency and simplification of ELISA tests for rapid and ultrasensitive detection of okadaic acid in shellfish", Food control, Impact Factor: 2.738   
42. W. Haider, D. Barillier, A. Hayat, J-L. Gaillard, J. Ledauphin (2013), "Rapid quantification and comparison of major volatile compounds of ciders from France (Normandy and Brittany) using micrextraction by packed sorbent (MEPS)", Analytical methods, Impact Factor: 1.855   
43. A. Hayat, C. Yang, A. Rhoutai, J-L. Marty (2013), "Recent advances and achievements in nanomaterial-based, and structure switchable aptasensing platforms for ochratoxin A detection", Sensors, Impact Factor: 1.953   
44. A. Hayat, L. Barthelmebs, J-L. Marty (2012), "A simple colorimetric enzymatic-assay for okadaic acid detection based on the immobilization of protein phosphatase 2A in sol-gel", Applied biochemistry and biotechnology, Impact Factor: 1.893   
45. R-B. Dominguez, A. Hayat, A. Sassolas, G-A. Alonso, R. Munoz, J-L. Marty (2012), "Automated flow-through amperometric immunosensor for highly sensitive and on-line detection of okadaic acid in mussel sample", Talanta, Impact Factor: 3.498   
46. A. Hayat, L. Barthelmebs, A. Sassolas, J-L. Marty (2012), "Development of a novel label-free amperometric immunosensor for the detection of okadaic acid", Anal Chim Acta , Impact Factor: 4.387   
47. A. Hayat, L. Barthelmebs, J-L. Marty (2012), "Electrochemical impedimetric immunosensor for the detection of okadaic acid in mussel sample", Sens. Actuat. B, Impact Factor: 3.535   
48. A. Hayat, J-L. Marty, A-E. Radi (2012), "Novel Amperometric Hydrogen Peroxide Biosensor Based on Horseradish Peroxidase Azide Covalently Immobilized on Ethynyl-Modified Screen-Printed Carbon Electrode via Click Chemistry", Electroanalysis, Impact Factor: 2.817   
49. A. Hayat, N. Paniel, A. Rhoutai, J-L. Marty, L. Barthelmebs (2012), "Recent advances in ochratoxin A-producing fungi detection based on PCR methods and ochratoxin A analysis in food matrices", Food control, Impact Factor: 2.738   
50. A. Hayat, L. Barthelmebs, A. Sassolas, J-L. Marty (2011), "An electrochemical immunosensor based on covalent immobilization of okadaic acid onto screen printed carbon electrode via diazotization-coupling reaction", Talanta, Impact Factor: 3.498   
51. A. Sassolas, G. Catanante, A. Hayat, J-L. Marty (2011), "Development of an efficient protein phosphatase-based colorimetric test for okadaic acid detection", Anal Chim Acta, Impact Factor: 4.387   
52. L. Barthelmebs, A. Hayat, A-W. Limiadi, J-L. Marty, T. Noguer (2011), "Electrochemical DNA aptamer-based biosensor for OTA detection, using superparamagnetic nanoparticles", Sens. actuat. B, Impact Factor: 3.535   
53. L. Barthelmebs, J. Jonca, A. Hayat, B-P. Simon, J-L. Marty (2011), "Enzyme-Linked Aptamer Assays (ELAAs), based on a competition format for a rapid and sensitive detection of Ochratoxin A in wine", Food control, Impact Factor: 2.738   
54. A. Hayat, L. Barthelmebs, J-L. Marty (2011), "Enzyme-linked immunosensor based on super paramagnetic nanobeads for easy and rapid detection of okadaic acid", Anal Chim Acta, Impact Factor: 4.387   

Qualification

Post Doc
Clarkson University, New York, USA
2013
   
PhD
University of Perpignan, IMAGES, Perpignan, France
2012
   
M.S
University of Perpignan, France
2009
   
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