Dr. Anila Asif
Professor, IRCBM
Area of Interest: Polymer Chemistry, Biomaterials
Tel # (Off): 111-001-007   (291)

Dr Anila Asif has strong background in polymer chemistry and physics and her research interests span a wide range with a focus on the processing-structure-properties relation in polymers  (hyperbranched/ dendrimers), composites and bioceramics.

In terms of techniques, she has particular expertise in the use of FTIR spectrophotometer, Photo-DSC, UV curing, TGA, DSC, DMA, GPC, VPO and UV-Vis spectrophotometer.

Her research group at IRCBM focuses on synthesis of porous bioceramic, polymer /ceramic composite materials. Major ongoing projects in her group are listed below.

Macroporous bioceramic monoliths for hard tissue replacement; synthesis, characterization and in vitro analysis:

Calcium phosphates bioceramics, especially hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), are excellent candidates for bone repair and regeneration. Two main forms of HA, dense and porous play an eminent role for bone regeneration. However porous HA provides more directed in-growth of bone cells. So aim of this project is to synthesize porous bioceramics with pore morphology in consistent with pore characteristics of natural bone. Moreover biological evaluation of synthesized porous ceramic will ensure its use as a clinically safe bone substitute.

Synthesis and characterization of novel composite materials:

Hydroxyapatite has been widely used as an auspicious bone graft due to its similarity with inorganic constituent of human bone, excellent biocompatibility and osteoconductivity. But poor mechanical strength of Hydroxyapatite restricts its application to non loaded areas. So its composites with different polymers are commonly employed for load bearing applications. She has particular interest in developing methods of synthesizing materials and processes in situ, experiments focusing on synthesis composite of Hydroxyapatite with Poly vinyl alcohol to get mechanically improved bone substitute are in progress. Synthesis of bone replacement materials with good biological and mechanical properties will make possible their short hand availability in Pakistan and will definitely help to improve the quality of life. 

Synthesis of bioceramic 3D scaffolds for guided bone generation:

A key component for successful bone regeneration is the scaffold that serves as a template for cell interactions and the formation of bone-extracellular matrix to provide structural support to the newly formed tissue. Recently she has been at the forefront of research into the development of novel bioceramic scaffolds. Ultimate aim is to get scaffolds with mechanical properties similar to those of the bone repair site, good biocompatibility and biodegradability at a rate commensurate with remodeling.

 

Publications:

Book Chapters:
1. Anila Asif, Hongbo Liang, Shengwu Zhu, Wenfang Shi. (2006), "Synthesis and degradation mechanism of UV curable flame retardants containing phosphorus for coatings", Photochemistry and UV curing: new trends, Standard: ISBN: 81-308-0014-4.   
Journal Papers:
1. Naseer Iqbal, Abdul Samad Khan, Anila Asif, Muhammad Yar, John W Haycock, Ihtesham Ur Rehman, (2019), " “Recent concepts in biodegradable polymers for tissue engineering paradigms: A critical review” ", Internation Materials Reviews, pp: 91-126, Vol: 64, Issue: 2, Impact Factor: 12.703   
2. Faiza Sharif, Sobia Tabassum, Waleed Mustafa, Anila Asif, Faiza Zarif, Muhammad Tariq, Saadat Anwar Siddiqui, Mazhar A. Gilani, Ihtesham Ur Rehman, Sheila MacNeil (2018), "“Bioresorbable Antibacterial PCL-PLA-nHA Composite Membranes for Oral and Maxillofacial Defects” ", Polymer Composites, Vol: DOI 10.1002/pc.24899, Impact Factor: 1.943   
3. Jinxing Chen, Kun Zeng, Mozhen Wang, Anila Asif, and Xuewu Ge (2017), " “Catalase-imprinted Fe3O4/Fe@fibrous SiO2/polydopamine nanoparticles: An integrated nanoplatform of magnetic targeting, magnetic resonance imaging, and dual-mode cancer therapy” ", Nano Research, pp: 2351–2363, Vol: 10, Issue: 7, Impact Factor: 7.994   
4. Jinxing Chen, Kun Zeng, Mozhen Wang, Anila Asif, and Xuewu Ge (2017), ""The Molecular Imprinted Nanotrapper for Catalase: A Chemical-Free Inhibition Way to Trigger Tumor Cells Apoptosis”", Particle and Particle System Characterization , pp: 1600260, Vol: 34, Impact Factor: 4.384   
5. Fu-Xing Lin, Juan Xie, Kun Zeng , Mo-Zhen Wang, Anila Asif , Xue-wu Ge (2017), "Chitosan modified by ?-ray-induced grafting of poly(tributyl-(4-vinylbenzyl) phosphonium) as the biosafe and high-efficiency gene carrier", New Journal of Chemistry , pp: 4182—4189 , Vol: 41, Impact Factor: 3.269    (External URL)
6. Jie Wang, Mozhen Wang, Anila Asif, Qichao Wu, Xiao Zhou, and Xuewu Ge (2017), "Monodisperse Polypyrrole Nanoparticles Prepared via ?-Ray Radiolysis of Water: An Efficient Near-Infrared Photothermal Agent for Cancer Therapy", Particle and Particle System Characterization, pp: 1600430, Vol: 34, Impact Factor: 4.384   
7. Riaz Hussain, Sobia Tabassum, Mazhar Amjad Gilani, Ejaz Ahmad, Ahsan Sharif, Faisal Manzoor, Asma Tufail Shah, Anila Asif, Faiza Sharif, Farasat Iqbal, Saadat Anwar Siddiqi, (2016), "“ In situ synthesis of mesoporous polyvinyl alcohol / hydroxyapatite composites for better biomedical coating adhesion”", Applied Surface Science, pp: 117–123, Vol: 364, Impact Factor: 2.711    (External URL)
8. Ayesha Sohail, Khadija Maqbool, Anila Asif, Haroon Ahmad (2015), "“Numerical Modeling of Effective Diffusivity in Bone Tissue Engineering”", International Journal of Medical, Health, Biomedical, Bioengineering and Pharmaceutical Engineering , pp: 82-86, Vol: 9, Issue: 1    (External URL)
9. 3. M. Anis-ur-Rehman, Fatima-tuz-Zahra, Seemab Kanwal, Anila Asif, Anam Noor Hussain, Saba Zahid, (2015), "“Study of dielectric relaxations in co-precipitated Sr–Fe(Cr) nanoferrites”", Journal of Material Science: Material in Electronics, pp: 6539-6545, Vol: 26 , Issue: 9, Impact Factor: 1.569    (External URL)
10. Mamoona Bashir , Malik Sajjad Mehmood , Anila Asif , and Masroor Ikram (2015), "Analysis of pulse laser induced modifications on HDPE for laser processing of polyethylene”", Journal of Russian Laser Research,, pp: 258-268., Vol: 36, Impact Factor: 0.546    (External URL)
11. Anila Asif , Rabia Nazir, Tehseen Riaz , Nafisa Ashraf, Saba Zahid, Ramla Shahid, Anis Ur-Rehman, Aqif Anwar Chaudhry, Ihtesham Ur Rehman (2014), "Influence of processing parameters and solid concentration on microstructural properties of gel-casted porous hydroxyapatite", Journal of Porous Materials, pp: 31-37, Vol: 21, Impact Factor: 1.108    (External URL)
12. Nida Iqbal, Rabia Nazir, Anila Asif, Aqif A. Chaudhry, Muhammad Akram, Goh Yi Fan, Aftab Akram, Rashid Amin, Sung Ha Park, Rafaqat Hussain (2012), "Electrophoretic deposition of PVA coated hydroxyapatite on 316 L stainless steel", Current Applied Physics , pp: 755-759, Vol: 12 , Issue: (3)   
13. Rabia Nazir, Nida Iqbal, Abdul S. Khan, Aftab Akram, Anila Asif, Aqif A. Chaudhry, Ihtesham ur. Rehman, Rafaqat Hussain. (2012), "Rapid synthesis of thermally stable hydroxyapaptite", Ceramics International, pp: 457-462., Vol: 38 , Issue: (1)   
14. Yong Zhang, Anila Asif, Wenfang Shi (2011), "Highly branched polyurethane acrylates and their waterborne UV curing coating", Progress in Organic Coatings, pp: 295-301, Vol: 71 , Issue: ( 3)   
15. Ligen Qiao, Anila Asif, Wenfang Shi. (2011), "Synthesis and characterization of shape memory material based on hyperbranched polyurethane-tetrazole", Science China Chemistry , pp: 1461-1467, Vol: 54, Issue: (9) , Standard: 0717-3644    
16. Lihua Hu, Anila Asif, Jianda Xie, Wenfang Shi (2011), "Synthesis and photoinitiating behavior of hyperbranched polymeric photoinitiators bearing coinitiator amine", Polymer for Advanced Technologies, pp: 1673-1680., Vol: 12, Standard: 1042-7147     (External URL)
17. Fu Zhan, Anila Asif, Wenfang Shi (2010), "Synthesis and Properties of Cationic Photopolymerizable Hyperbranched Polyesters with Terminal Oxetane Groups by the Couple-monomer Polymerization of Carboxylic Anhydride with Hydroxyl Oxetane", POLYMER, pp: 3402-3409, Vol: 51, Issue: 15, Standard: 0717-3644     (External URL)
18. Anila Asif, Lihua Hu, Wenfang Shi. (2009), "Synthesis, Rheological and Thermal Properties of Waterborne Hyperbranched Polyurethane Acrylate Dispersions for UV Curable Coatings", Colloid & Polymer Science , pp: 1041-1049, Vol: 287, Issue: 9, Standard: 0303-402X    
19. Muhammad Sadiq Subhani, Anila Ikram, Rumana Qureshi and Abdur Rehman (2008), "Investigation of Resonance Effect, Inductive Effect, Solvation Energies and Electron Affinities of Some Thiosemicarbazides, Hydrazides and Carboxylic Acids through Linear Scan Voltammetry", Journal of The Chemical Society of Pakistan , pp: 209-213, Vol: 30, Issue: 2, Standard: 0253-5106   
20. Hongbo Liang, Anila Asif, Wenfang Shi (2005), "Photopolymerization and thermal behaviors of phosphate diacrylate and triacrylate used as reactive-type flame retardant monomers in UV curable resins", Journal of Applied Polymer Science , pp: 185-194, Vol: 97, Issue: 1, Standard: 0021-8995    
21. Anila Asif, Chengyu Huang, Wenfang Shi (2005), "Photopolymerization of waterborne polyurethane acrylate dispersions based on hyperbranched aliphatic polyester and properties of the cured films", Colloid & Polymer Science , pp: 721-730, Vol: 283, Issue: 7, Standard: 0303-402X    
22. Anila Asif, Wenfang Shi, Xiaofeng Shen, Kangming Nie (2005), "Physical and thermal properties of UV curable waterborne polyurethane dispersions incorporating hyperbranched aliphatic polyester of varying generation number", Polymer, pp: 11066-11078., Vol: 46, Issue: 24, Standard: 0717-3644     (External URL)
23. Hongbo Liang, Anila Asif, Wenfang Shi (2005), "Thermal degradation and flame retardancy of a novel methacrylated phenolic melamine used for UV curable flame retardant coatings", Degradation and Stability, pp: 185-194, Vol: 87, Issue: 3, Standard: 0141-3910   
24. Huigang Kou, Anila Asif, Wenfang Shi, Jiang ZW, Huang WH (2004), "A novel hyperberbranched polyester acrylate used for microfabrications", Polymers for Advanced Technologies, pp: 192-196, Vol: 15, Issue: 4, Standard: 1042-7147    
25. Anila Asif, Chengyu Huang, Wenfang Shi (2004), "Structure–property study of waterborne, polyurethane acrylatete dispersions based on hyperbranched aliphatic polyester for UV-curable coatings", Colloid & Polymer Science , pp: 200-208, Vol: 283, Issue: 2, Standard: 0303-402X    
26. Anila Asif, Jianhua Liu, Wenfang Shi (2004), "The status of UV radiation curing markets and technology in China", JCT CoatingsTech, pp: 56-61, Vol: 1, Issue: 4, Standard: 1547-0083   
27. Anila Asif, Wenfang Shi (2004), "UV curable waterborne polyurethane acrylate dispersions based on hyperbranched aliphatic polyester: effect of molecular structure on physical and thermal properties", Polymers for Advanced Technologies, pp: 669-675, Vol: 15, Issue: 11, Standard: 1042-7147    
28. Huigang Kou, Anila Asif, Wenfang Shi. (2003), "Hyperbranched acrylated aromatic polyester used as a modifier in UV-curable epoxy acrylate resins", Chinese Journal of Chemistry, pp: 91-95, Vol: 21, Issue: 1, Standard: 1614-7065   
29. Huigang Kou, Anila Asif, Wenfang Shi. (2003), "Photopolymerization kinetics of hyperbranched acrylated aromatic polyester", Journal of Applied Polymer Science, pp: 1500-1504, Vol: 89, Issue: 6, Standard: 0021-8995    
30. Anila Asif, Wenfang Shi (2003), "Synthesis and properties of UV curable waterborne hyperbranched aliphatic polyester", European Polymer Journal, pp: 933-938, Vol: 39, Standard: 0014-3057   
31. Anila Asif, Chengyu Huang, Wenfang Shi. (2003), "UV Curing Behaviors and Hydrophilic Characteristics of UV Curable Waterborne Hyperbranched Aliphatic Polyesters", Polymers for Advanced Technologies, pp: 609-615, Vol: 14, Issue: 9, Standard: 1042-7147    
32. Huigang Kou, Anila Asif, Wenfang Shi. (2002), "Photopolymerizable acrylated hyperbranched polyisophthalesters used for photorefractive materials I. Synthesis and characterization", European Polymer Journal, pp: 1931-1936, Vol: 38, Issue: 10, Standard: 0014-3057   

Qualification

Post doc
Centre for Biomaterials and Tissue Engineering Department of Materials Science and Engineering , Kroto Research Institute, University of Sheffield, Sheffield, UK
2015
   
PhD
University of Science and Technology of China, Hefei, P.R. China
2005
   
MPhil
Quaid-i-Azam University, Islamabad, Pakistan
1997
   
MSc
Quaid-i-Azam University, Islamabad, Pakistan
1995
   
BSc
Lahore College for Women University, Lahore, Pakistan
1992
   

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