Dr. Ayaz Hassan
Assistant Professor, IRCBM
Area of Interest: 2D graphene based electrochemical sensors and biosensors, In-situ spectroscopy of biological molecules, Biofuel cells, Nanomaterials
Tel # (Off): 111-001-007  

Publications:

Journal Papers:
1. H. Ullah, M. Akram, A. Hassan, H. Khan, M. Irfan, G. Sinani, Z. Ulker (2025), "Sodium Aliginate Carboxymethyl Cellulose Composite Hydrogel Beads for Oral Drug Delivery", ChemistrySelect, pp: 1-9, Vol: 10, Impact Factor: 2   
2. A. Muhaddas, A. Ijaz, G. Abbas, A. Hayat, A. Rahim, A. Hassan (2025), "In-situ synthesis of bimetallic-MOF/porous graphene oxide nanocomposite for electrochemical sensing of ascorbic acid", Microchemical Journal, pp: 114759, Vol: 216, Impact Factor: 5.1   
3. M. Irfan, U. Haider, M. Irfan, H. H. Makki, M. Kouki, H. A. Garalleh, A. A Agha, A. Hassan (2025), "Aminopropyltrimethoxysilane immobilized silanol based polyurethane nanofiltration membrane for salt separation", Emergent Materials, pp: 00, Vol: 00, Impact Factor: 4.1   
4. Ayaz Hassan, Filipe C. D. A. Lima, Frank N. Crespilho (2025), "Redox-Guided DNA Scanning by the Dynamic Repair Enzyme Endonuclease III", Biochemistry, pp: 782-790, Vol: 64, Issue: 4, Impact Factor: 3.0   
5. M. Naeem Shabbir, Adeel Ahmad, Muhammad Aslam, Ayaz Hassan, Hidayat Ullah, Muhammad Akram, Hafiza Fatima Qayum, Fatima Naeem (2024), "Chemically modified filter paper with Jaman fruit extract for visual sensing of milk freshness", Food Chemistry, pp: 142161, Vol: 466, Impact Factor: 9.8   
6. Ayesha Ijaz, Ayesha Muhaddas, Muhammad Zeeshan Farooq, Rizwan Wahab, Muhammad H. Aziz, Akhtar Hayat, Ayaz Hassan (2024), "Development of a Sensitive Cysteine-Modified Au-NPs-Graphene Nanoribbons Nanocomposite Disposable Biosensor for Aflatoxin B1 Detection in Food samples", ACS Applied Nano Materials, pp: 25556, Vol: 7, Impact Factor: 5.5   
7. Muhammad Z. Farooq, Muhammad Akram, Masooma Irfan, Hidayat Ullah, Muhammad Tariq, Muhammad Yasir, Ayaz Hassan (2024), "A three-components-based disposable electrochemical sensor for the detection of heavy metal ions in water", Diamond & Related Materials, pp: 111718, Vol: 150, Impact Factor: 5.1   
8. Adeel Ahmad, Muhammad Naeem Shabbir, Muhammad Irfan, Ayaz Hassan (2024), "A fast response colorimetric sensor based on food color for ammonia detection", Emergent Materials, Vol: 8, Impact Factor: 4.1   
9. Ayaz Hassan, Daniel S. de Sousa, Thiago Bertaglia, Frank N. Crespilho (2024), "An enhanced label free detection of proteins on gold nanoparticles micropatterns for surface enhanced infrared absorption spectroscopy", ChemComm, pp: 7212-7215, Vol: 60, Impact Factor: 4.2   
10. Shaista I. Khan, Hassan, A, Rehana Bano, Mazhar A. Gilani, Jean L. Marty, Hongxia Zhang, Akhtar Hayat (2023), "An innovative and universal dual-signal ratiometric spectroelectrochemical imprinted sensor design for sandwich type detection of anticancer-drug, gemcitabine, in serum samples; cross validation via computational modeling", Talanta, pp: 125233, Vol: 267, Impact Factor: 6.1   
11. Hassan, A, Rafael N. P. Colombo, Rodrigo M. Iost, Frank N (2023), "Amplifying sensing performance through gold micropatterns-induced modulation of graphene's vertical electron transfer", Electrochimica Acta, pp: 143069, Vol: 466, Impact Factor: 5.6   
12. Hassan, A, Isabela A. Mattioli, Rafael N. P. Colombo, Frank N. Crespilho (2023), "Tuning quantum capacitance in 2D graphene electrodes: the role of defects and charge carrier concentration", Journal of Material Chemistry C, pp: 6301-6305, Vol: 11, DOI: https://doi.org/10.1039/D2TC04037A, Impact Factor: 5.1   
13. Mian A. Ali, Graziela C. Sedenho, Jessica C. Pacheco, Rodrigo M. Iost, Asma Rahman, Ayaz Hassan, Daniel R. Cardoso, Roberto S. Gomes, Frank N. Crespilho (2022), "Metal-free, low-cost, and high-performance membraneless ethanol fuel cell", Journal of Power Sources, pp: 232164, Vol: 551, Impact Factor: 9.719   
14. Graziela C. Sedenho, Ayaz Hassan, João C. P. de Souza, and Frank N. Crespilho (2022), "In situ and operando electrochemistry of redox enzymes", Current Opinion in Electrochemistry, pp: 101015, Vol: 34, Impact Factor: 7.271   
15. Ihsan Ullah, Abdur Rab, Abdur Rahim, Muhammad Tariq, Ayaz Hassan, Tawfik. A. Saleh, Jehangeer Khan & Hizb Ullah Khan (2022), "The stimulus role of lithium sulfate (Li2SO4) on the electrical and mechanical properties of poly (vinyl alcohol)-MWCNTS-based thin film composites", Journal of Material Science: Materials in Electronics, pp: 18157–18166, Vol: 33, Impact Factor: 2.478   
16. Lucyano J. A. Macedo, Fernando P. Rodrigues, Ayaz Hassan, Leandro N. C. Máximo, Fabio Zobi, Roberto S. da Silva, and Frank N. Crespilho (2021), "Non-destructive molecular FTIR spectromicroscopy for real time assessment of redox metallodrugs", Analytical Methods, pp: 1094-1102, Vol: 14, Impact Factor: 3.532   
17. Isabela A. Mattiolia, Ayaz Hassan, Natalia M. Sanches, Nirton C.S. Vieira, Frank N. Crespilho (2021), "Highly sensitive interfaces of graphene electrical-electrochemical vertical devices for on drop atto-molar DNA detection", Biosensors and Bioelectronics, pp: 112851, Vol: 175, Impact Factor: 12.54   
18. Graziela C.Sedenho, AyazHassan, Lucyano J.A.Macedo, Frank N.Crespilho (2021), "Stabilization of bilirubin oxidase in a biogel matrix for high-performance gas diffusion electrodes", Journal of Power Sources, pp: 229035, Vol: 482, Impact Factor: 9.719   
19. Dr. Ayaz Hassan, Dr. Graziela C. Sedenho, Phelipe A. M. Vitale, Mona N. Oliviera, Prof. Frank N. Crespilh (2021), "On the Weak Binding and Spectroscopic Signature of SARS-CoV-2 nsp14 Interaction with RNA", ChemBioChem, pp: 3410-3413, Vol: 22, Issue: 24, Impact Factor: 3.461   
20. Natalia M. Sanches, Ayaz Hassan, Isabela A. Mattioli, Lucyano J. A. Macedo, Graziela C. Sedenho, Frank N. Crespilho (2021), "Tuning Vertical Electron Transfer on Graphene Bilayer Electrochemical Devices", Advance Materials Interfaces, pp: 2100550, Vol: 8, Issue: 20, Impact Factor: 6.389   
21. Lucyano J. A. Macedo, Anderson A. E. Santo, Graziela C. Sedenho, Ayaz Hassan, Rodrigo M. Iost, Gustavo T. Feliciano, Frank N.Crespilho (2021), "Three-dimensional catalysis and efficient bioelectrocatalysis beyond surface chemistry", Journal of Catalysis, pp: 200-205, Vol: 401, Impact Factor: 8.047   
22. Ayaz Hassan, Lucyano J.A.Macedo, Isabela A. Mattiolia, Rafael J. G. Rubirab, Carlos J. L. Constantino, Rodrigo G. Amorim, Filipe C.D.A.Lima, Frank N.Crespilho (2021), "A three component-based van der Waals surface vertically designed for biomolecular recognition enhancement", Electrochimica Acta, pp: 138025, Vol: 376, Impact Factor: 6.901   
23. João C. P. de Souza,Lucyano J. A. Macedo, Ayaz Hassan, Graziela C. Sedenho, Iago A. Modenez, Frank N. Crespilho (2021), "In Situ and Operando Techniques for Investigating Electron Transfer in Biological Systems", ChemElectroChem, pp: 431-446, Vol: 8, Issue: 3, Impact Factor: 4.782   
24. Isabela A. Mattioli, Ayaz Hassan, Osvaldo N. Oliveira Jr., and Frank N. Crespilho (2020), "On the challenges for the diagnosis of SARS-COV-2 based on a review of current methodologies", ACS Sensors, pp: 3655-3677, Vol: 5, Issue: 12, Impact Factor: 7.711   
25. Ayaz Hassan, Lucyano J. A. Macedo and Frank N. Crespilho (2020), "Recognizing conductive islands in polymeric redox surfaces using electrochemical-coupled vibrational spectromicroscopy", ChemComm, pp: 10309-10312, Vol: 56, Impact Factor: 6.222   
26. Amanda Hikari Imamura, Thiago Pinotti Segato, Letícia Jordão Marques de Oliveira, Ayaz Hassan, Frank Nelson Crespilho & Emanuel Carrilho (2020), "Monitoring cellulose oxidation for protein immobilization in paper-based low-cost biosensors", Microchimica Acta, pp: 1-8, Vol: 272, Impact Factor: 6.232   
27. Ayaz Hassan, Lucyano J. A. Macedo, João C. P. de Souza, Filipe C. D. A. Lima & Frank N. Crespilho (2020), "A combined Far-FTIR, FTIR Spectromicroscopy, and DFT Study of the Effect of DNA Binding on the [4Fe4S] Cluster Site in EndoIII", Scientific Report, pp: 1-12, Vol: 1931, Issue: 10, Impact Factor: 4.996   
28. Lucyano J. A. Macedo, Ayaz Hassan, Graziela C. Sedenho & Frank N. Crespilho (2020), ". Assessing electron transfer reactions and catalysis in multicopper oxidases with operando X-ray absorption spectroscopy", Nature Communications, pp: 1-7, Vol: 316, Issue: 11, Impact Factor: 17.69   
29. Muhammad Haris Mehmood, Muhammad Tariq, Ayaz Hassan, Abdul Raziq, Abdur Rahim and Jehangeer Khan (2019), "Facile solvothermal synthesis of Pt–Cu nanocatalyst with improved electrocatalytic activity toward methanol oxidation", Journal of Serbian Chemical Society, pp: 1155-1167, Vol: 84, Issue: 10, Impact Factor: 1.24   
30. Mian A. Ali, Ayaz HassanAyaz Hassan São Carlos Institute of ChAyaz Hassan , Graziela C. Sedenho, Renato V. Gonçalves, Daniel R. Cardoso, and Frank N. Crespilho (2019), "Operando Electron Paramagnetic Resonance for Elucidating the Electron Transfer Mechanism of Coenzymes", Journal of Physical Chemistry C, pp: 16058-16064, Vol: 123, Issue: 26, Impact Factor: 4.126   
31. Antonio F. A. A. MeloAntonio F. A. A. Melo São Carlos Institute of Chemistry, University of São Paulo, São Carlos 13560-970, São Paulo, Brazil World Premier International (WPI) Research Center for Materials Nanoarchitectonics (Antonio F. A. A. Melo, (2019), "Microwires of Au–Ag Nanocages Patterned via Magnetic Nanoadhesives for Investigating Proteins using Surface Enhanced Infrared Absorption Spectroscopy", Applied Materials and Interfaces, pp: 18053–18061, Vol: 11, Issue: 20, Impact Factor: 10.38   
32. Tiago B. Becher, Carolyne B. Braga, Diego L. Bertuzzi, Miguel D. Ramos, Jr, Ayaz Hassan, Frank N. Crespilho and Catia Ornelas (2018), "Structure-Property Relationship in Laponite Materials: From Wigner Glasses to Strong Self-Healing Hydrogels Formed by Non-Covalent Interactions", Soft Matter, pp: 1278-1289, Vol: 15, Impact Factor: 4.046   
33. Ayaz Hassan and Edson Antonio Ticianelli (2018), "Activity and Stability of Dispersed Multi Metallic Pt-based Catalysts for CO Tolerance in Proton Exchange Membrane Fuel Cell Anodes", Annals of Brazilian Academy of Sciences, pp: 1-22, Vol: 90, Impact Factor: 1.73   
34. Lucyano J. A. Macedo, Rodrigo M. Iost, Ayaz Hassan, Kannan Balasubramanian, and Frank N. Crespilho (2018), "Bioelectronics and Interfaces Using Monolayer Graphene", ChemElectroChem, pp: 1-30, Vol: 5   
35. Mohd. Khalid, Ayaz Hassan, Ana M. B. Honorato, Frank N. Crespilho and Hamilton Varela (2018), "Nano-flocks of a bimetallic organic framework for efficient hydrogen evolution electrocatalysis", ChemComm, pp: 11048, Vol: 54   
36. Abdul Raziq, Muhammad Tariq, Riaz Hussian, Muhammad Haris Mehmood, Muhammad Saleem Khan, and Ayaz Hassan (2017), "Electrochemical Investigation of Glucose Oxidation on a Glassy Carbon Electrode Using Voltammetric, Amperometric, and Digital Simulation Methods", Chemistry Select, pp: 9711– 9717, Vol: 2, Impact Factor: 2.307   
37. Ayaz Hassan, Valdecir A. Paganin, Edson A. Ticianelli (2016), "Investigation of carbon-supported PtW catalysts as CO-tolerant anodes at high temperature in proton exchange membrane fuel cell", Journal of Power Sources, pp: 375-382, Vol: 325, Impact Factor: 9.719   
38. Ayaz Hassan, Valdecir Antonio Paganin, Edson Antonio Ticianelli (2015), "Pt modified tungsten carbide as anode electrocatalyst for hydrogen oxidation in proton exchange membrane fuel cell: CO tolerance and stability", Applied Catalysis B: Environmental, pp: 611-619, Vol: 165, Impact Factor: 24.319   
39. Ayaz Hassan, Valdecir Antonio Paganin, Edson Antonio Ticianelli (2015), "Effect of Addition of Ru and/or Fe in the Stability of PtMo/C Electrocatalysts in Proton Exchange Membrane Fuel Cells", Electrocatalysis, pp: 512-520, Vol: 6, Impact Factor: 2.713   
40. Ayaz Hassan, Alejo Carreras, Jorge Trincavelli, Edson Antonio Ticianelli (2014), "Effect of heat treatment on the activity and stability of carbon-supported PtMo alloy electrocatalysts for hydrogen oxidation in proton exchange membrane fuel cells", Journal of Power Sources, pp: 712-720, Vol: 247, Impact Factor: 9.719   
41. Ayaz Hassan, Valdecir Antonio Paganina, Alejo Carrerasb, Edson Antonio Ticianelli (2014), "Molybdenum carbide-based electrocatalysts for CO tolerance in proton exchange membrane fuel cell anodes", Electrochimica Acta, pp: 307-316, Vol: 142, Impact Factor: 6.901   

Qualification

PhD
University of São Paulo, Brazil
Feb 2011 to Feb 2015
   

Experience

Postdoctoral Fellow
University of São Paulo
Apr 2017 to Mar 2021
   
Assistant Professor
National Center of Excellence in Physical Chemistry
Sep 2015 to Mar 2017
   

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