Dr. Madiha Saeed
Assistant Professor, IRCBM
Area of Interest: Nanomedicine Based Cancer Therapy, such as Cancer Photothermal Therapy, Photodynamic Therapy, and Immunotherapy.
Tel # (Off): 111-001-007  

Publications:

Book Chapters:
1. Madiha Saeed, Aiguo Wu (2020), "Biosensor for Swine Influenza Virus", Recent Trends in Nanobiosensors Research: From Design to Applications, published by: Wiley VCH, Standard: 9783527345106: 311-327   
2. Gohar I. Dar, Madiha Saeed, Aiguo Wu (2020), "Toxicity of TiO2 Nanoparticles", TiO2 Based Nanobiotechnology and Nanomedicine, published by: Wiley VCH, Standard: 9783527347247: 67-103   
Journal Papers:
1. Xiaoying Liu#, Fangmin Chen#, Madiha Saeed#, Xutong Li#, Huijuan Zhang, Jiangying Zhang, Mingyue Zheng, Feng Wang*, Hui Wang*, Haijun Yu* (2024), "In-situ vaccination immunotherapy of colorectal cancer with STING agonist-integrated supramolecular nanovectors", Nano Today, pp: 102273, Vol: 56, Impact Factor: 17.4    
2. Shunan Zhang#, Yi Lai#, Jiaxing Pan#, Madiha Saeed, Shiqin Li, Huiling Zhou, Xingyu, Jiang, Jing Gao, Yun Zhu, Haijun Yu*, Wen Zhang*, Zhiai Xu* (2024), "PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer", Advanced Materials, DOI: https://doi.org/10.1002/adma.202314132, Impact Factor: 29.4    
3. Farukh Mansoor, Huangxian Ju, Madiha Saeed, Shamsa Kanwal (2023), "Facile synthesis of gold nanocages with silver nanocubes templates dual metal effects enabled SERS imaging and catalytic reduction", RSC Advances, pp: 31366, Vol: 13   
4. Weiqi Wang, Qiwen Zhu, Yilan Jin, Jing Gao, Jianan Li, Xiaohua Zheng, Weidong Gao, Madiha Saeed*, Weizhong Sheng*, Haijun Yu*. (2023), "Self-Immolated Nanoadjuvant for In Situ Vaccination Immunotherapy of Colorectal Cancer. ", Advanced Healthcare Materials, DOI: 10.1002/adhm.202300524, Impact Factor: 11.092   
5. Fangmin Chen, Tianliang Li, Huijuan Zhang, Madiha Saeed, Xiaoying Liu, Lujia Huang, Xiyuan Wang, Jing Gao, Yi Lai, Zhiai Xu, Zuoquan Xie, Min Luo, Haijun Yu*. (2023), "Acid-ionizable iron nanoadjuvant augments STING activation for personalized vaccination immunotherapy of cancer", Advanced Materials, pp: 2209910, Vol: 35, DOI: 10.1002/adma.202209910, Impact Factor: 32.086   
6. Yike Hou, Tang Zhe, Jabeen Farheen, Madiha Saeed, Lijia Luo, Wenzi Ren, Dandan Luo, Asim Mushtaq, Ruibo Zhao, Jian Ge, Zhangsen Yu, Yao Li, M. Zubair Iqbal, Xiangdong Kong. (2023), "Ovalbumin-loaded paramagnetic nano-triangles for enhanced dendritic cell stimulation, T1-MR imaging, and antitumor immunity.", Journal of Materials Science & Technology, pp: 123-137, Vol: 148, Impact Factor: 10.319   
7. Fenglin Li; Yi Lai; Jiayi Ye; Madiha Saeed; Yijing Dang; Zhifeng Zou; Fangmin Chen; Wen Zhang, Zhiai Xu (2022), "Dual-targeting prodrug nanotheranostic for NIR-? fluorescence imaging-guided photo-immunotherapy of glioblastoma", Acta Pharmaceutica Sinica B, DOI: https://doi.org/10.1016/j.apsb.2022.05.016, Impact Factor: 14.903   
8. Jiayi Ye#, Bo Hou#, Madiha Saeed*, Zhiai Xu*, Haijun Yu*. (2022), "Engineering Bioinspired Nanomedicines for Mitigating Resistance of Cancer Immunotherapy", Accounts of Materials Research, pp: 697, Vol: 3, DOI: https://doi.org/10.1021/accountsmr.2c00042, Impact Factor: 14.6   
9. Tianliang Li#, Rundi Song#, Fang Sun, Madiha Saeed, Xiaozhen Guo, Jiayi Ye, Bo Hou, Fangmin Chen, Cen Xie, Zhiai Xu, Huixiong Xu, Haijun Yu (2022), "Bioinspired magnetic nanocomplexes amplifying STING activation of the tumor-associated macrophages to potentiate cancer immunotherapy", Nano Today, DOI: https://doi.org/10.1016/j.nantod.2022.101400, Impact Factor: 18.962   
10. Rundi Song#, Tianliang Li#, Jiayi Ye, Fang Sun, Madiha Saeed, Bo Hou, Jing Gao, Miaomiao Wu, Qiwen Zhu, Zhiai Xu, Haijun Yu (2021), "Acidity-activatable Dynamic Nanoparticles Boosting Ferroptotic Cell Death for Immunotherapy of Cancer", Advanced Materials, DOI: https://doi.org/10.1002/adma.202101155, Impact Factor: 32.086   
11. Madiha Saeed, Fangming Chen, Yang Shi, Twan Lammers, Bruno De Geest, Zhiping Xu, Haijun Yu (2021), "From design to clinic: Engineered nanobiomaterials for immune normalization therapy of cancer", Advanced Materials (Featured as a cover), Impact Factor: 32.086    (External URL)
12. Yi Lai, Fenglin Li, Zhifeng Zou, Madiha Saeed, Zhiai Xua, Haijun Yu (2021), "Bio-inspired amyloid polypeptides: from self-assembly to nanostructure design and biotechnological applications", Applied Materials Today, DOI: https://doi.org/10.1016/j.apmt.2021.100966, Impact Factor: 8.663   
13. Fangmin Chen#, Yingjie Wang#, Jing Gao, Madiha Saeed, Tianliang Li, Weiqi Wang, Haijun Yu (2021), "Nanobiomaterial-based vaccination immunotherapy of cancer", Biomaterials, DOI: https://doi.org/10.1016/j.biomaterials.2021.120709, Impact Factor: 15.304   
14. Fang Sun#, Qiurong Zhu#, Tianliang Li, Madiha Saeed, Zhiai Xu, Feisheng Zhong, Rundi Song, Manxiu Huai, Mingyue Zheng, Cen Xie, Leiming Xu, Haijun Yu (2021), "Regulating Glucose Metabolism with Prodrug Nanoparticles for Promoting Photoimmunotherapy of Pancreatic Cancer", Advanced Science, DOI: https://doi.org/10.1002/advs.202002746, Impact Factor: 17.521   
15. Qiwen Zhu, Madiha Saeed, Rundi Song, Tao Sun, Chen Jiang, Haijun Yu (2020), "Dynamic covalent chemistry-regulated stimuli-activatable drug delivery systems for improved cancer therapy", Chinese Chemical Letters, DOI: https://doi.org/10.1016/j.cclet.2019.12.002, Impact Factor: 8.455   
16. Khizra Bano, Sadia Zafar Bajwa, Ayesha Ihsan, Irshad Hussain, Nuzhat Jameel, Asma Rehman, Ayesha Taj, Sumaira Younus, M Zubair Iqbal, Faheem K Butt, Madiha Saeed, Thomas J Webster, Waheed S Khan (2020), "Synthesis of SPIONs-CNT Based Novel Nanocomposite for Effective Amperometric Sensing of First-Line Antituberculosis Drug Rifampicin", Journal of Nanoscience and Nanotechnology, DOI: https://doi.org/10.1166/jnn.2020.17204, Impact Factor: 1.354   
17. Bo Hou#, Lei Zhou#, Hui Wang#, Madiha Saeed, Dangge Wang, Zhiai Xu, Yaping Li, Haijun Yu (2020), "Engineering Stimuli-Activatable Boolean Logic Prodrug Nanoparticles for Combination Cancer Immunotherapy", Advanced Materials, DOI: https://doi.org/10.1002/adma.201907210, Impact Factor: 32.086   
18. Xianli Hu#, Bo Hou#, Zhiai Xu, Madiha Saeed, Fang Sun, Zhenmei Gao, Yi Lai, Tong Zhu, Fan Zhang, Wen Zhang, Haijun Yu (2020), "Supramolecular Prodrug Nanovectors for Active Tumor Targeting and Combination Immunotherapy of Colorectal Cancer", Advanced Science, DOI: https://doi.org/10.1002/advs.201903332, Impact Factor: 17.521   
19. Yi Lai, Yingying Zhu, Zhiai Xu, Xianli Hu, Madiha Saeed, Haijun Yu, Xingxing Chen, Jun Liu, Wen Zhang (2020), "Engineering Versatile Nanoparticles for Near-Infrared Light-Tunable Drug Release and Photothermal Degradation of Amyloid ß", Advanced Functional Materials, DOI: https://doi.org/10.1002/adfm.201908473, Impact Factor: 19.924   
20. Madiha Saeed, Zhiai Xu, Bruno G. De Geest, Huixiong Xu, Haijun Yu (2020), "Molecular imaging for cancer immunotherapy: Seeing is believing", Bioconjugate Chemistry, DOI: https://doi.org/10.1021/acs.bioconjchem.9b00851, Impact Factor: 6.069   
21. Ang Gao, Binfan Chen, Jing Gao, Fengqi Zhou, Madiha Saeed, Bo Hou, Yaping Li, Haijun Yu (2019), "Sheddable Prodrug Vesicles Combating Adaptive Immune Resistance for Improved Photodynamic Immunotherapy of Cancer", Nano Letters, DOI: https://doi.org/10.1021/acs.nanolett.9b04012, Impact Factor: 12.262   
22. Madiha Saeed, Sadia Zafar Bajwa, Imdad Kaleem, Asma Rehman, Khizra Bano, Bushra Tehseen, Nuzhat Jamil, Mehvish Zahoor, Ayesha Shaheen, Ayesha Taj, M. Rizwan Younis, Waheed S. Khan (2019), "Assessment of Antimicrobial Features of Selenium Nanoparticles (SeNPs) Using Cyclic Voltammetric Strategy", Journal of Nanoscience and Nanotechnology, DOI: https://doi.org/10.1166/jnn.2019.16627, Impact Factor: 1.354   
23. Madiha Saeed, Jing Gao, Yang Shi, Twan Lammers, Haijun Yu (2019), "Engineering Nanoparticles to Reprogram the Tumor Immune Microenvironment for Improved Cancer Immunotherapy", Theranostics, DOI: https://doi.org/10.7150/thno.37568, Impact Factor: 11.6    (External URL)
24. Ang Gao, Xianli Hu, Madiha Saeed, Binfan Chen, Yaping Li, Haijun Yu (2019), "Overview of recent advances in liposomal nanoparticle-based cancer immunotherapy", Acta Pharmacologica Sinica, DOI: https://doi.org/10.1038/s41401-019-0281-1, Impact Factor: 7.169   
25. Bing Feng,# Bo Hou,# Zhiai Xu, Madiha Saeed, Haijun Yu, Yaping Li (2019), "Self-Amplified Drug Delivery with Light-Inducible Nanocargoes to Enhance Cancer Immunotherapy", Advanced Materials, DOI: https://doi.org/10.1002/adma.201902960, Impact Factor: 32.086   
26. Ozioma U. Akakuru, M. Zubair Iqbal, Madiha Saeed, Chuang Liu, Tatjana Paunesku, Gayle Woloschak, Narayan S. Hosmane, Aiguo Wu (2019), "The Transition from Metal-Based to Metal-Free Contrast Agents for T 1 Magnetic Resonance Imaging Enhancement", Bioconjugate Chemistry. , DOI: https://doi.org/10.1021/acs.bioconjchem.9b00499, Impact Factor: 6.069   
27. Weiqi Wang, Madiha Saeed, Yao Zhou, Lili Yang, Dangge Wang, Haijun Yu (2019), "Non-viral gene delivery for cancer immunotherapy", Journal of Gene Medicine, DOI: https://doi.org/10.1002/jgm.3092, Impact Factor: 4.152   
28. Madiha Saeed, M. Zubair Iqbal, Wenzhi Ren, Yuanzhi Xia, Waheed S. Khan, Aiguo Wu (2018), "Tunable fabrication of new theranostic Fe3O4-black TiO2 nanocomposites: dual wavelength stimulated synergistic imaging-guided phototherapy in cancer", Journal of Materials Chemistry B, DOI: https://doi.org/10.1039/C8TB02704H, Impact Factor: 7.571   
29. M. Zubair Iqbal, Wenzhi Ren, Madiha Saeed, Tianxiang Chen, Xuehua Ma, Xu Yu, Jichao Zhang, Lili Zhang, Aiguo Li, Aiguo Wu (2018), "A facile fabrication route for binary transition metal oxide-based Janus nanoparticles for cancer theranostic applications", Nano Research, DOI: https://doi.org/10.1007/s12274-017-1628-x, Impact Factor: 10.269   
30. Chuang Liu, Lijia Luo, Leyong Zeng, Jie Xing, Yuanzhi Xia, Shan Sun, Luyun Zhang, Zhe Yu, Junlie Yao, Zhangsen Yu, Ozioma Akakuru, Madiha Saeed, Aiguo Wu (2018), "Porous Gold Nanoshells on Functional NH2-MOFs: Facile Synthesis and Designable Platforms for Cancer Multiple Therapy", Small, DOI: https://doi.org/10.1002/smll.201801851, Impact Factor: 13.281   
31. Siqi Wang, Wenzhi Ren, Jianhua Wang, Zhenqi Jiang, Madiha Saeed, Lili Zhang, Aiguo Li, Aiguo Wu (2018), "Black TiO2-based nanoprobes for T1-weighted MRI-guided photothermal therapy in CD133 high expressed pancreatic cancer stem-like cells", Biomaterials Science, DOI: DOI https://doi.org/10.1039/C8BM00454D, Impact Factor: 7.590   
32. M. Usman Munir, Ayesha Ihsan, Yasra Sarwar, Sadia Zafar Bajwa, Khizra Bano, Bushra Tehseen, Neelam Zeb, Irshad Hussain, M. Tayyab Ansari, Madiha Saeed, Juan Li, M. Zubair Iqbal, Aiguo Wu, Waheed S. Khan (2018), "Hollow mesoporous hydroxyapatite nanostructures; smart nanocarriers with high drug loading and controlled releasing features", International Journal of Pharmaceutics, DOI: https://doi.org/10.1016/j.ijpharm.2018.04.029, Impact Factor: 6.510   
33. Madiha Saeed, M. Zubair Iqbal, Wenzhi Ren, Yuanzhi Xia, Chuang Liu, Waheed S. Khan, Aiguo Wu (2018), "Controllable synthesis of Fe3O4 nanoflowers: enhanced imaging guided cancer therapy and comparison of photothermal efficiency with black-TiO2", Journal of Materials Chemistry B, DOI: DOI https://doi.org/10.1039/C8TB00745D, Impact Factor: 7.571   
34. Farooq Aziz, Khizra Bano, Ahmad Hassan Siddique, Sadia Zafar Bajwa, Aalia Nazir, Anam Munawar, Ayesha Shaheen, Madiha Saeed, Muhammad Afzal, M. Zubair Iqbal, Aiguo Wu, Waheed S. Khan (2018), "Lecithin-coated gold nanoflowers (GNFs) for CT scan imaging applications and biochemical parameters; in vitro and in vivo studies", Artificial cells, Nanomedicine, and Biotechnology, DOI: https://doi.org/10.1080/21691401.2017.1423496, Impact Factor: 6.355   
35. Madiha Saeed Wenzhi Ren, Aiguo Wu (2017), "Therapeutic applications of iron oxide based nanoparticles in cancer: basic concepts and recent advances", Biomaterials Science (Featured as Back Cover) , DOI: https://doi.org/10.1039/C7BM00999B, Impact Factor: 7.590   
36. Madiha Saeed, Asma Rehman, Ayesha Ihsan, Sadia Z. Bajwa, Khizra Bano, Waheed S. Khan (2016), "Growth of Highly Stable Selenium Nanoparticles (SeNPs) Using Polyvinyl Alcohol and 4-Aminoantipyrine and Their Optical Properties", Journal of Nanoengineering and Nanomanufacturing, DOI: https://doi.org/10.1166/jnan.2016.1291   

Qualification

Ph.D. (CAS-TWAS awardee)
University of Chinese Academy of Sciences , China
Sep 2014 to Jun 2018
   
M.Phil. Biotechnology
Pakistan Institute of Engineering and Applied Sciences (PIEAS), Islamabad (NIBGE Campus), Pakistan
Oct 2011 to Dec 2013
   

Experience

Assistant Professor
COMSATS University Islamabad, Lahore Campus
May 2022 to Date
   
Visiting Scientist under an International Talent Program of the CAS, that is, the CAS President’s International Fellowship Initiative
Shanghai Institute of Materia Medica
Jul 2023 to Mar 2024
   
Postdoctoral under CAS President’s International Fellowship Initiative (PIFI) Program
Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences (CAS). China
Apr 2019 to Jun 2021
   

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