Dr. Muhammad Ihtisham Umar
Tenured Associate Professor, Pharmacy
Area of Interest: Molecular Pharmacology of drugs that target pro-angiogenic and tumor cell survival signalling.
Tel # (Off): 111-001-007  

Dr. Muhammad Ihtisham Umar is currently working as Assistant Professor in the Department of Pharmacy, COMSATS Lahore campus. He completed his Bachelors in Pharmacy degree from the College of Pharmacy, University of the Punjab Lahore in 2005 and Masters of Philosophy in Pharmacology from the Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences Lahore in 2008. In 2010, he moved to Malaysia to pursue his doctoral studies from the School of Pharmaceutical Sciences, Universiti Sains Malaysia (USM) that is one of the top ranked Malaysian Universities. He completed his PhD in Pharmacology from USM in 2014 that was funded by USM Fellowship Scheme. Dr. Ihtisham is HEC approved PhD supervisor. His research interests include the anti-angiogenic and pro-apoptotic evaluation of drugs with special focus on their molecular mechanism. 

Publications:

Journal Papers:
1. Iqbal A, Khan ZA, Shahzad SA, Khan SA, Naqvi SAZ, Bari A, Amjad H, Umar MI (2019), "Synthesis, modeling studies and evaluation of E-stilbene hydrazides as potent anticancer agents", Journal of Molecular Structure, pp: 271-281, Vol: 1197, Impact Factor: 2.12   
2. Iqbal J, Ejaz SA, Ibrar A, Umar MI, Lecka J, Sévigny J, Saeed A (2018), "Expanding the Alkaline Phosphatase Inhibition, Cytotoxic and Proapoptotic Profile of Biscoumarin-Iminothiazole and Coumarin-Triazolothiadiazine Conjugates", ChemistrySelect, pp: 13377-86, Vol: 3, Issue: 47, Impact Factor: 1.505   
3. Jafari B, Rashid F, Safarov S, Ospanov M, Yelibayeva N, Abilov ZA, Turmukhanova MZ, Kalugin SN, Ehlers P, Umar MI, Zaib S, Iqbal J, Langer P (2018), "Synthesis of Novel Benzothiazolo[3,2-a]pyridimidin-4-ones with Potential Cytotoxic and Pro-Apoptotic Potential", chemistryselect , pp: 12213-8, Vol: 3, Issue: 43, ISSN: 2365-6549, Impact Factor: 1.505   
4. Umar MI, Iqbal MA, Ahamed MBK, Altaf R, Hassan LEA, Haque RA, Majeed AMSA, Asmawi MZ (2018), "Cytotoxic and Pro-Apoptotic Properties of Ethyl-p-Methoxycinnamate and Its Hydrophilic Derivative Potassium-p-Methoxycinnamate", Chemistry Africa, pp: 1-9, Vol: https://doi.org/10.1007/s42250-018-0010-z, ISSN: ISSN: 2522-5758 (Print) 2522-5766 (Online)   
5. Altaf R, Umar MI, Mohd Zaini Asmawi, Amirin Sadikun, Aidiahmad Dewa, Nurul Maizan Manshor, Nadiah Razali, Haroon Khalid Syed, Mohamed Khadeer Ahamed Basheer (2018), "Polar components of Phaleria macrocarpa fruit exert antihypertensive and vasorelaxant effects by inhibiting arterial tone and extracellular calcium influx", Pharmacognosy Magazine, pp: 312-321, Vol: 14, Issue: 56, ISSN: ISSN : 0973-1296, Impact Factor: 1.525   
6. Huda NU, Islam S, Zia M, William K, Abbas FI, Umar MI, Iqbal MA, Mannan A (2018), "Anticancer, antimicrobial and antioxidant potential of sterically tuned bis-N-heterocyclic salts", Zeitschrift fur Naturforschung C, Impact Factor: 0.882   
7. Faizullah M., Rahman N., Umar M.I. , Anwar M., Sarfraz M. (2017), "A cross-sectional study on knowledge, attitude and practices of medical doctors towards antibiotic prescribing patterns and resistance in Khyber Pakhtun Khawah, Pakistan", Journal of Applied Pharmaceutical Science, pp: 038-046, Vol: 7, Issue: 12, Impact Factor: 0.69   
8. Seow, L. J., Beh, H. K., Umar, M.I., Sadikun, A., Asmawi, M. Z. (2016), "Anti-angiogenic activities of the standardised methanol extract of Gynura segetum leaf", Asian Journal of Ethnopharmacology and Medicinal Foods, pp: 19-25, Vol: 2, Issue: 4  Abstract 
9. Hassan LEA, Dahham SS, Fadul SM, Umar MI, Majid ASA, Khaw KY, Majid AMSA (2016), "Evaluation of in vitro and in vivo anti-inflammatory effects of (-)-pseudosemiglabrin, a major phytoconstituent isolated from Tephrosia apollinea (Delile) DC", Journal of Ethnopharmacology, pp: 312-320, Vol: 193, Impact Factor: 3.115   
10. Iqbal, M.A., Umar, M.I., Haque, R.A., Ahamed, M.K.B., Asmawi, M.Z., Abdul Majeed, A. M. S. (2015), "Macrophage and colon tumor cells are targets for a binuclear silver (I) N-heterocyclic carbine complex, an anti-inflammatory and apoptotic mediator", Journal of inorganic Biochemistry, pp: 1-13, Vol: 146, Impact Factor: 3.063   
11. Hussein, M.A., Iqbal, M.A., Umar, M.I., Haque, R.A., Guan, T.S. (2015), "Synthesis, structural elucidation and cytotoxicity of new thiosemicarbazone derivatives", Arabian Journal of Chemistry, pp: doi.org/10.1016/j.arabjc.2015.08.013, Vol: in press, Impact Factor: 2.969   
12. Seow, L. J., Beh, H. K., Umar, M.I., Sadikun, A., Asmawi, M. Z. (2014), "Anti-inflammatory and antioxidant activities of the methanol extract of Gynura segetum leaf", International Immunopharmacology, pp: 186-191, Vol: 23, Issue: 1, Impact Factor: 3.118   
13. Umar, M.I., Asmawi, M.Z., Sadikun, A., Abdul Majeed, A. M. S., Ahamed, M.K.B., Al-Suede, F.S.R., Hassan, L.E.A., Altaf, R. (2014), "Ethyl-p-methoxycinnamate isolated from Kaempferia galanga inhibits inflammation by suppressing IL-1, TNF-a and angiogenesis by blocking endothelial functions", Clinics, pp: 134-144, Vol: 69, Issue: 2   
14. Jafari, S. F, Ahamed, M. B. K., Iqbal, M. A., Al Suede, F. S. R., Syed, H. K., Haque, R. A., Nassar, Z. D., Umar, M.I., Majid, A. M. S. A. (2014), "Increased aqueous solubility and pro-apoptotic activity of potassium koetjapate against human colorectal cancer cells", Journal of Pharmacy and Pharmacology, pp: 1394-1409, Vol: 66 , Issue: 10, Impact Factor: 2.309   
15. Umar, M.I., Asmawi, M.Z., Sadikun, A., Abdul Majid, A.M.S., Atangwho, I.J., Bashir, M.K.A., Altaf, R., Ahmad, A. (2014), "Multiconstituent synergism is responsible for anti-inflammatory effect of Azadirachta indica A. Juss leaf extract", Pharmaceutical Biology, pp: 1411-22, Vol: 52, Issue: 11, Impact Factor: 1.918   
16. Atangwho, I.J., Yin, K.B., Umar, M.I., Ahmad, M., Asmawi, M.Z. (2014), "Vernonia amygdalina simultaneously suppresses gluconeogenesis and potentiates glucose oxidation via the pentose phosphate pathway in streptozotocin-induced diabetic rats", BMC Complementary and Alternative Medicine, pp: 426, Vol: 14, Impact Factor: 2.109   
17. Altaf, R., Asmawi, M. Z., Dewa, A., Sadikun, A., & Umar, M.I. (2013), "Phytochemistry and medicinal properties of Phaleria macrocarpa (Scheff.) Boerl. extracts", Pharmacognosy Reviews, pp: 73-80, Vol: 7   
18. Umar, M.I., Javeed, A., Ashraf, M., Riaz, A., Mukhtar, M. M., Afzal, S., & Altaf, R. (2013), "Polarity- based solvents extraction of opuntia dillenii and zingiber officinale for in vitro antimicrobial activities", International Journal of Food Properties, pp: 114-124, Vol: 16, Issue: 1, Impact Factor: 1.845   
19. Haque, R. A., Iqbal, M. A., Asekunowo, P., Majid, A. M. S. A., Ahamed, M. B. K., Umar, M.I., Al-Ravi, S.S., Al-Suede, F. S. R. (2013), "Synthesis, structure, anticancer, and antioxidant activity of paraxylyl linked bis-benzimidazolium salts and respective dinuclear Ag (I) N-heterocyclic carbene complexes (Part-II)", Medicinal Chemistry Research, pp: 4663-4676, Vol: 22, Impact Factor: 1.607   
20. Umar, M.I., Asmawi, M. Z., Sadikun, A., Atangwho, I. J., Yam, M. F., Altaf, R., & Ahmed, A. (2012), "Bioactivity-guided isolation of ethyl-p-methoxycinnamate, an anti-inflammatory constituent, from Kaempferia galanga L. extracts", Molecules, pp: 8720-8734, Vol: 17, Impact Factor: 3.098   
21. Ahmad, A., Khan, A. H., Atif, M., Umar, M.I., Syed, H. K., Malik, N. S., & Usman, A. (2012), "Precautionary measurements and rationale use of antibiotics in diabetic foot ulcer can save amputation: A case report", African Journal of Pharmacy and Pharmacology, pp: 1569-1572, Vol: 6, Issue: 22   
22. Altaf, R., Asmawi, M. Z., Dewa, A., & Umar, M.I. (2012), "Sources and possible mechanisms of action of important phytoconstituents with cardiovascular properties", African Journal of Pharmacy and Pharmacology, pp: 563-580, Vol: 6, Issue: 9   
23. Khan, A. H., Zakaria, A. D., Sulaiman, S. A. S., Umar, M.I., & Redhuan, N. E. Y. (2012), "The perioperative use of ceftriaxone as infection prophylaxis in neurosurgery: carnioplasty", Journal of Pharmaceutical and Scientific Innovation, pp: 27-28, Vol: 1, Issue: 5   
24. Umar, M.I., Asmawi, M. Z. B., Sadikun, A., Altaf, R., & Iqbal, M. A. (2011), "Phytochemistry and medicinal properties of Kaempferia galanga L. (Zingiberaceae) extracts", African Journal of Pharmacy and Pharmacology, pp: 1638-1647, Vol: 5, Issue: 14   
25. Umar, M.I., Altaf, R., Iqbal, M. A., & Sadiq, M. B. (2010), "in vivo experimental models to investigate the anti-inflammatory activity of herbal extracts", Science International, pp: 199-203, Vol: 22, Issue: 3   

Qualification

Ph.D. Pharmacology
School of Pharmaceutical Sciences, University of Science, Malaysia
Jul 2010 to Nov 2014
   
M. Phil Pharmacology
Department of Pharmacology and Toxicology, University of Veterinary and Animal Sciences Lahore, Pakistan
Apr 2006 to Mar 2008
   
B. Pharmacy
College of Pharmacy, University of The Punjab (Old Campus) Lahore, Pakistan
Feb 2001 to Dec 2005
   

Experience

Assistant Professor
Department of Pharmacy, COMSATS Institute of Information Technology
Jan 2018 to Date
   
Assistant Professor
Department of Pharmacy, COMSATS Institute of Information Technology Abbottabad
Dec 2015 to Dec 2016
   
Assistant Professor
College of Pharmacy, University of Hail Saudi Arabia
Nov 2014 to Sep 2015
   
Research Fellow
University of Science Malaysia
Jan 2011 to Dec 2013
   
Lecturer
University of South Asia Lahore
Oct 2008 to May 2010
   
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