Dr. Hafiza Fakhera Ikram
Associate Professor, IRCBM
Area of Interest: Molecular Oncology, Molecular Genetics, Cell Biology, Biotechnology, Biochemistry, Tissue Engineering, 3D Printing
Tel # (Off): 111-001-007  

Dr. Fakhera Ikram is an Assistant Professor at Interdisciplinary Research Center in Biomedical Materials (IRCBM) COMSATS Institute of Information Technology, Lahore. Her research interests lie primarily in the area of Molecular Oncology, Biotechnology and Biochemistry. Her spectrum of methods is broad and includes deep sequencing techniques, primer designing, cloning, retroviral gene transfer, lentiviral shRNA knockdown, cell cycle analysis by FACS, immunofluorescence, western blotting and functional analyses. Previously, she worked on molecular basis of autosomal recessive deafness at Centre of Excellence in Molecular Biology (CEMB), University of the Punjab, Lahore. At the University of Cologne (Germany), her research was focused of “Identification and Characterization of Genetic Alterations in Neuroblastoma and their Prognostic Relevance”. During her postdoctoral period, she worked on identification of fusion-transcripts in neuroblastoma. Dr. Ikram has published her research in a range of reputed journals, including Nature. She has presented her research in many international conferences and symposia. She has been the winner of best oral presenation award in the category of basic science in Adnvances in Neuroblastoma Research (ANR 2014) meeting which was held in May 2014 in Cologne, Germnay. She also won the lerner Family Foundation Early Career Travel award to participate in “Advances in Neuroblastoma 2016 Meeting”, held in June 19-23, 2016 in Cairns, Queensland, Australia. Her current research focuses on understanding the molecular mechanisms of deadly disease, cancer. Currently, she is keen to investigate the molecular mechanism of cytotoxicity induced by metal nanoparticles in various cancer cell lines and animal models.

Publications:

Journal Papers:
1. Yunis Moukbil, Busra Isindag, Velican Gayir, Burak Ozbek, Merve Erginer Haskoylu, Ebru Toksoy Oner, Faik NuzhetOktar, Fakhera Ikram, Mustafa Sengor, Oguzhan Gunduz. (2019), "3D printed bioactive composite scaffolds for bone tissue engineering", Bioprinting, Vol: 17, Impact Factor: 2.6    (External URL)
2. Hamad Khalid, Saba Zahid, Fakhera Ikram, Haffsah Iqbal, Muhammad Samie, Lubna Shahzadi, Asma Tufail Shah, Muhammad Yar, Aqif Anwar Chaudhry, Sana Awan, Ather Farooq Khan, Ihtesham Rehman. (2019), "Bi-layered a-tocopherol acetate loaded membranes for potential wound healing and skin regeneration", Materials Science & Engineering, pp: 438-447, Vol: 101, Issue: 10, Impact Factor: 5.0   
3. Mehmet Onur Aydogdu, Ebru Toksoy Oner, Nazmi Ekren, Gokce Erdemir, Serap Erdem Kuruca, Esra Yuca Muge, Sennaroglu Bostan, Mehmet S.Eroglu, Fakhera Ikram, Muhammet Uzun, OguzhanGunduz. (2019), "Comparative characterization of the hydrogel added PLA/ß-TCP scaffolds produced by 3D bioprinting.", Bioprinting, Vol: 13, Impact Factor: 2.6    (External URL)
4. Asif Ali, Farasat Iqbal, Akhlaq Ahmad, Fakhera Ikram, Anaum Nawaz, Aqif Anwar Chaudhry, Saadat Anwar Siddiqi, Ihetesham ur Rehman. (2019), "Hydrothermal deposition of high strength calcium phosphate coatings on magnesium alloy for biomedical applications. ", Surface and Coatings Technology, pp: 716-727, Vol: 357, Impact Factor: 2.9    (External URL)
5. Asma Tufail Shah,, Saba Zahid, Fakhera Ikram, Muhammad Maqbool, Aqif Anwar Chaudhry, Muhammad Imran Rahim, Franziska Schmidt, Oliver Goerke, Abdul Samad Khan, Ihtesham ur Rehman. (2019), "Tri-layered functionally graded membrane for potential application in periodontal regeneration. ", Materials Science & Engineering: C., Vol: 103, Impact Factor: 5.0    (External URL)
6. Sandra Ackermann, Maria Cartolano, Barbara Hero, Anne Welte, Yvonne Kahlert, Andrea Roderwieser, Christoph Bartenhagen, Esther Walter, Judith Gecht, Laura Kerschke, Ruth Volland, Roopika Menon, Johannes M. Heuckmann, Moritz Gartlgruber, Sabine Hartli (2018), "A mechanistic classification of clinical phenotypes in neuroblastoma.", Science, pp: 1165-1170, Vol: 362, Issue: 6419, Impact Factor: 41.05    (External URL)
7. Aysenur Topsakal, Muhammet Uzun, Gaye Ugar, Aslihan Özcan, Esra Altun, F. Nüzhet Oktar, Fakhera Ikram, Oguzhan Gündüz, HilalTürkoglu Sasmazel, Ozan Özkan (2018), "Development of Amoxicillin-Loaded Electrospun Polyurethane/Chitosan/ß-Tricalcium Phosphate Scaffold for Bone Tissue Regeneration,", IEEE Transactions on NanoBioscience., Standard: 1536-1241, Impact Factor: 2.15   
8. Fakhera Ikram, Sandra Ackermann, Yvonne Kahlert, Ruth Volland, Frederik Roels, Anne Engesser, Falk Hertwig, Hayriye Kocak, Barbara Hero, Daniel Dreidax, Kai-Oliver Henrich, Frank Berthold, Peter Nürnberg, Frank Westermann and Matthias Fischer (2016), "Transcription factor activating protein 2 beta (TFAP2B) mediates noradrenergic neuronal differentiation in neuroblastoma", Molecular Oncology, Vol: 2, Issue: 10, Impact Factor: 5.3   
9. Martin Peifer, Falk Hertwig, Frederik Roels, Daniel Dreidax, Moritz Gartlgruber, Roopika Menon, Andrea Krämer, Justin L. Roncaioli, Frederik Sand, Johannes M. Heuckmann, Fakhera Ikram, Rene Schmidt, Sandra Ackermann, Anne Engesser, Yvonne Kahlert, We (2015), "Telomerase activation by genomic rearrangements in high-risk neuroblastoma.", Nature, pp: 4, Vol: 526, Issue: 7575, Impact Factor: 41.2   

Qualification

Post-Doctorate
Department of Pediatric Oncology and Hematology, University Children`s Hospital, Cologne, Germany
Dec 2014 to Dec 2015
   
Ph.D
Cologne Centre for Genomics (CCG), University of Cologne, Cologne, Germany
Oct 2009 to Dec 2014
   
M.Phil
Centre of Excellance in Molecular Biology (CEMB), University of the Punjab, Lahore, Pakistan
Jan 2008 to Jul 2010
   
B.S (Hons)
Department of Zoology, University of the Punjab, Lahore, Pakistan
Jun 2003 to Jun 2007
   
F.Sc (Pre-Medical)
Government College for Women, Gulberg, Lahore, Pakistan
Jul 1999 to Sep 2001
   
Matric
Government Girls High School, Kangan Pur, Kasur, Pakistan
Jan 1997 to Jun 1999
   

Experience

Assistant Professor
COMSATS Institute of Information Technology, Lahore, Pakistan
Oct 2016 to Date
   
Assistant Professor
Centre for Apllied Molecular Biology (CAMB), University of the Punjab, Lahore
Jan 2016 to Oct 2016
   
Post-Doctorate
Department of Pediatric Oncology and Hematology, University Children`s Hospital, Cologne, Germany
Dec 2014 to Dec 2015
   

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